EPIFIX®
Dehydrated Human Amnion/Chorion Membrane A llograft

EPIFIX is a placental tissue allograft composed of dehydrated human amnion/chorion membrane (DHACM). It is available in sheet and mesh/fenestrated configurations in a variety of sizes to reduce wastage.
EPIFIX is backed by the most Level I publications among placental-based allografts
The quality of MIMEDX RCTs was evaluated and validated in an assessment initiated by the Agency of Healthcare Research & Quality.¹
Product Advantages
EPIFIX is the amniotic skin substitute with an unprecedented depth of clinical data support.

Protective Environment
EPIFIX acts as a barrier to protect the wound bed to aid in the development of granulation tissue in acute and chronic closures

Outcomes
Demonstrated statistically significant outcomes vs. SOC solutions & other skin substitutes

Regulatory Proteins
EPIFIX provides a biocompatible human extracellular matrix and contains 300+ regulatory proteins 2-4

Versatility
Multiple configurations available for varying demands depending on wound or surgical application desired

Compatibility
Compatible with negative pressure wound therapy (NPWT) and hyperbaric oxygen therapy (HBOT)

Easy to Store
Simple storage and application
Snyder DL, Sullivan N, Margolis DJ, Schoelles K. Skin substitutes for treating chronic wounds. Technology Assessment Program Project ID No. WNDT0818. (Prepared by the ECRI Institute-Penn Medicine Evidence-based Practice Center) Rockville, MD: Agency for Healthcare Research and Quality. https://www.cms.gov/Medicare/Coverage/DeterminationProcess/downloads/id109TA.pdf. Published February 2020. Accessed February 20, 2022.
Koob TJ, Lim JJ, Massee M, Zabek N, Denozière G. Properties of dehydrated human amnion/chorion composite grafts: Implications for wound repair and soft tissue regeneration. J Biomed Mater Res B Appl Biomater. 2014;102(6):1353-1362.
Lei J, Priddy LB, Lim JJ, Massee M, Koob TJ. Identification of Extracellular Matrix Components and Biological Factors in Micronized Dehydrated Human Amnion/Chorion Membrane. Adv Wound Care (New Rochelle). 2017;6(2):43-53.
MIMEDX Internal Report. MM-RD-00086, Proteome Characterization of PURION Processed Dehydrated Human Amnion Chorion Membrane (dHACM) and PURION PLUS Processed Dehydrated Human Umbilical Cord (dHUC) Allografts.